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Association Between Obesity, High-Sensitivity C-Reactive Protein ≥2 mg/L, and Subclinical Atherosclerosis
Author(s) -
Michael J. Blaha,
Juan J. Rivera,
Matthew J. Budoff,
Ron Blankstein,
Arthur Agatston,
Daniel H. O’Leary,
Mary Cushman,
Susan G. Lakoski,
Michael H. Criqui,
Moysés Szklo,
Roger S. Blumenthal,
Khurram Nasir
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.223768
Subject(s) - subclinical infection , c reactive protein , obesity , medicine , sensitivity (control systems) , inflammation , electronic engineering , engineering
High-sensitivity C-reactive protein (hsCRP) levels are closely associated with abdominal obesity, metabolic syndrome, and atherosclerotic cardiovascular disease. The Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) trial has encouraged using hsCRP ≥2 mg/L to guide statin therapy; however, the association of hsCRP and atherosclerosis, independent of obesity, remains unknown.

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