Increased Thrombin Generation Is Associated With Acute Ischemic Stroke but Not With Coronary Heart Disease in the Elderly
Author(s) -
Laure CarcaillonBentata,
Martine AlhencGelas,
Yannick Béjot,
Christian Spaft,
Pierre Ducimetière,
Karen Ritchie,
JeanFrançois Dartigues,
PierreYves Scarabin
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.111.223453
Subject(s) - medicine , cardiology , stroke (engine) , disease , ischemic stroke , thrombin , coronary heart disease , thrombin generation , ischemia , platelet , mechanical engineering , engineering
A high thrombin generation level has been associated with the risk of venous thrombosis. Whether changes in this biomarker are relevant to arterial disease remains unknown. We investigated the association of thrombin generation with coronary heart disease (CHD) and acute ischemic stroke (AIS) in the elderly.
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