Preventive Effects of Exenatide on Endothelial Dysfunction Induced by Ischemia-Reperfusion Injury via K ATP Channels
Author(s) -
Sang Jin Ha,
Weon Kim,
Jong Shin Woo,
JinBae Kim,
Soo–Joong Kim,
Woo-Shik Kim,
Myeong Kon Kim,
Xian Wu Cheng,
Kwon Sam Kim
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.222653
Subject(s) - exenatide , endothelial dysfunction , reperfusion injury , ischemia , medicine , cardiology , pharmacology , endocrinology , diabetes mellitus , type 2 diabetes
The purpose of this study was to evaluate whether exenatide administration can prevent impairment in endothelium-dependent vasodilatation induced by ischemia-reperfusion (IR) injury and whether this effect is mediated by K(ATP) channel opening.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom