Adenosine Derived From ADP Can Contribute to Inhibition of Platelet Aggregation in the Presence of a P2Y 12 Antagonist
Author(s) -
David Iyú,
Jackie R. Glenn,
Ann E. White,
Sue Fox,
Stan Heptinstall
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.219501
Subject(s) - adenosine , adenosine diphosphate , ticagrelor , chemistry , prasugrel , pharmacology , antagonist , platelet , platelet aggregation inhibitor , adenosine a1 receptor , p2y receptor , adenosine deaminase , medicine , biochemistry , endocrinology , receptor , adenosine receptor , biology , purinergic receptor , agonist , platelet aggregation , clopidogrel , aspirin
To investigate whether adenosine diphosphate (ADP)-derived adenosine might inhibit platelet aggregation, especially in the presence of a P2Y₁₂ antagonist, where the effects of ADP at the P2Y₁₂ receptor would be prevented.
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