Timing and Dose of Statin Therapy Define Its Impact on Inflammatory and Endothelial Responses During Myocardial Infarction | Zendy

Andrei C. Spósito | Zendy; Simone Nascimento dos Santos | Zendy; Eliana Cotta de Faria | Zendy; Dulcinéia Saes Parra Abdalla | Zendy; Luiza P. da Silva | Zendy; Alexandre A. Sousa Soares | Zendy; André V.T. Japiassú | Zendy; José C. Quinaglia e Silva | Zendy; José Antônio Franchini Ramires | Zendy; Otávio Rizzi Coelho | Zendy

Open Access

Timing and Dose of Statin Therapy Define Its Impact on Inflammatory and Endothelial Responses During Myocardial Infarction

Author(s) -

Andrei C. Spósito,

Simone Nascimento dos Santos,

Eliana Cotta de Faria,

Dulcinéia Saes Parra Abdalla,

Luiza P. da Silva,

Alexandre A. Sousa Soares,

André V.T. Japiassú,

José C. Quinaglia e Silva,

José Antônio Franchini Ramires,

Otávio Rizzi Coelho

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.110.218685

Subject(s) - simvastatin , medicine , statin , myocardial infarction , tumor necrosis factor alpha , brachial artery , cardiology , gastroenterology , c reactive protein , endocrinology , inflammation , blood pressure

Clinical trials of statins during myocardial infarction (MI) have differed in their therapeutic regimes and generated conflicting results. This study evaluated the role of the timing and potency of statin therapy on its potential mechanisms of benefit during MI.

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