Adiponectin Induces Vascular Smooth Muscle Cell Differentiation via Repression of Mammalian Target of Rapamycin Complex 1 and FoxO4 | Zendy

Min Ding | Zendy; Yi Xie | Zendy; Róbert Wágner | Zendy; Jin Yu | Zendy; Ana Catarina Ribeiro Carrao | Zendy; Lucinda S. Liu | Zendy; Anthony K. Guzman | Zendy; Richard J. Powell | Zendy; John Hwa | Zendy; Eva M. Rzucidlo | Zendy; Kathleen A. Martin | Zendy

Open Access

Adiponectin Induces Vascular Smooth Muscle Cell Differentiation via Repression of Mammalian Target of Rapamycin Complex 1 and FoxO4

Author(s) -

Min Ding,

Yi Xie,

Róbert Wágner,

Jin Yu,

Ana Catarina Ribeiro Carrao,

Lucinda S. Liu,

Anthony K. Guzman,

Richard J. Powell,

John Hwa,

Eva M. Rzucidlo,

Kathleen A. Martin

Publication year - 2011

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.110.216804

Subject(s) - p70 s6 kinase 1 , vascular smooth muscle , adiponectin , microbiology and biotechnology , protein kinase b , phosphorylation , medicine , pi3k/akt/mtor pathway , endocrinology , biology , signal transduction , pharmacology , insulin , insulin resistance , smooth muscle

The adipocyte-secreted hormone adiponectin exerts important cardioprotective and antidiabetic effects. Little is known about its effect on vascular smooth muscle cells (VSMC), key cells in restenosis, hypertension, and atherosclerosis.

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