Cosegregation of Aortic Root Atherosclerosis and Intermediate Lipid Phenotypes on Chromosomes 2 and 8 in an Intercross of C57BL/6 and BALBc/ByJ Low-Density Lipoprotein Receptor −/− Mice
Author(s) -
Ralph Burkhardt,
Simon Sündermann,
Doris Ludwig,
Uta Ceglarek,
Lesca M. Holdt,
Joachim Thiery,
Daniel Teupser
Publication year - 2011
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.213843
Subject(s) - locus (genetics) , biology , quantitative trait locus , phenotype , lipoprotein , genetics , medicine , chromosomal region , cholesterol , endocrinology , gene
We sought to identify novel atherosclerosis-modifying loci and their potential functional links in a genome-wide approach using cosegregation analysis of atherosclerosis and related intermediate phenotypes in mice.
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