FRNK Inhibition of Focal Adhesion Kinase–Dependent Signaling and Migration in Vascular Smooth Muscle Cells
Author(s) -
Yevgeniya E. Koshman,
Tae-Hoon Kim,
Miensheng Chu,
Steven J. Engman,
Rekha Iyengar,
Seth L. Robia,
Allen M. Samarel
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.212761
Subject(s) - focal adhesion , paxillin , phosphorylation , proto oncogene tyrosine protein kinase src , biology , ptk2 , tyrosine phosphorylation , microbiology and biotechnology , kinase , vascular smooth muscle , protein kinase a , endocrinology , mitogen activated protein kinase kinase , smooth muscle
To examine whether interference with FRNK targeting to focal adhesions (FAs) affects its inhibitory activity and tyrosine phosphorylation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom