Nitric Oxide Synthase Expression and Functional Response to Nitric Oxide Are Both Important Modulators of Circulating Angiogenic Cell Response to Angiogenic Stimuli | Zendy

Christian Heiß | Zendy; A. Schanz | Zendy; Nicolas Amabile | Zendy; Sarah Jahn | Zendy; Qiumei Chen | Zendy; Maelene L. Wong | Zendy; Tienush Rassaf | Zendy; Yvonne Heinen | Zendy; Miriam M. CorteseKrott | Zendy; William Grossman | Zendy; Yerem Yeghiazarians | Zendy; Matthew L. Springer | Zendy

Open Access

Nitric Oxide Synthase Expression and Functional Response to Nitric Oxide Are Both Important Modulators of Circulating Angiogenic Cell Response to Angiogenic Stimuli

Author(s) -

Christian Heiß,

A. Schanz,

Nicolas Amabile,

Sarah Jahn,

Qiumei Chen,

Maelene L. Wong,

Tienush Rassaf,

Yvonne Heinen,

Miriam M. CorteseKrott,

William Grossman,

Yerem Yeghiazarians,

Matthew L. Springer

Publication year - 2010

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.110.211581

Subject(s) - chemokinesis , nitric oxide , chemotaxis , medicine , nitric oxide synthase , endothelial stem cell , vasoprotective , endocrinology , angiogenesis , endothelium , nitric oxide synthase type iii , chemistry , cancer research , biochemistry , enos , receptor , in vitro

Circulating angiogenic cells (CACs), also termed endothelial progenitor cells, play an integral role in vascular repair and are functionally impaired in coronary artery disease (CAD). The role of nitric oxide (NO) in CAC function is poorly understood. We hypothesized that CAC migration toward angiogenic signals is modulated by both NO synthase (NOS) expression and functional response to NO.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research