Evidence for Active Regulation of Pro-Osteogenic Signaling in Advanced Aortic Valve Disease
Author(s) -
Jordan D. Miller,
Robert M. Weiss,
Kristine M. Serrano,
Lauren Castaneda,
Robert Brooks,
Kathy Zimmerman,
Donald D. Heistad
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.211029
Subject(s) - calcification , aortic valve , aortic valve stenosis , medicine , wnt signaling pathway , stenosis , cardiology , endocrinology , valvular heart disease , signal transduction , biology , microbiology and biotechnology
To test the hypothesis that valvular calcium deposition, pro-osteogenic signaling, and function can be altered in mice with advanced aortic valve disease.
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