Endothelium-Dependent Coronary Vasodilatation Requires NADPH Oxidase-Derived Reactive Oxygen Species
Author(s) -
Jun Feng,
Scott M. Damrauer,
Monica Lee,
Frank W. Sellke,
Christiane Ferran,
M. Ruhul Abid
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.209726
Subject(s) - nadph oxidase , endothelium , protein kinase b , superoxide , reactive oxygen species , vasodilation , endothelial dysfunction , nitric oxide synthase , medicine , biology , nitric oxide , chemistry , endocrinology , biochemistry , phosphorylation , enzyme
To determine the functional significance of physiological reactive oxygen species (ROS) levels in endothelium-dependent nitric oxide (NO)-mediated coronary vasodilatation.
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