Inhibition of p38 Mitogen-Activated Protein Kinase Reduces Inflammation After Coronary Vascular Injury in Humans | Zendy

Lea SarovBlat | Zendy; John M. Morgan | Zendy; Pedro Fernández | Zendy; Rachel James | Zendy; Zixing Fang | Zendy; Mark R. Hurle | Zendy; Charlotte A. Baidoo | Zendy; Robert N. Willette | Zendy; John J. Lepore | Zendy; Svend Eggert Jensen | Zendy; Dennis L. Sprecher | Zendy

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Inhibition of p38 Mitogen-Activated Protein Kinase Reduces Inflammation After Coronary Vascular Injury in Humans

Author(s) -

Lea SarovBlat,

John M. Morgan,

Pedro Fernández,

Rachel James,

Zixing Fang,

Mark R. Hurle,

Charlotte A. Baidoo,

Robert N. Willette,

John J. Lepore,

Svend Eggert Jensen,

Dennis L. Sprecher

Publication year - 2010

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.110.209205

Subject(s) - medicine , conventional pci , percutaneous coronary intervention , restenosis , c reactive protein , cardiology , inflammation , placebo , protein kinase a , p38 mitogen activated protein kinases , coronary artery disease , kinase , stent , myocardial infarction , pathology , biology , alternative medicine , microbiology and biotechnology

To evaluate whether a p38α/β mitogen-activated protein kinase inhibitor, SB-681323, would limit the elevation of an inflammatory marker, high-sensitivity C-reactive protein (hsCRP), after a percutaneous coronary intervention (PCI).

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