Dyslipidemia of Mothers With Familial Hypercholesterolemia Deteriorates Lipids in Adult Offspring
Author(s) -
Anouk van der Graaf,
Maud N. Vissers,
Daniel Gaudet,
Diane Brisson,
Suthesh Sivapalaratnam,
Tessa J. Roseboom,
Angelique C.M. Jansen,
John J.P. Kastelein,
Barbara A. Hutten
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.209064
Subject(s) - offspring , dyslipidemia , apolipoprotein b , familial hypercholesterolemia , medicine , endocrinology , pregnancy , cholesterol , fetus , cohort , biology , genetics , diabetes mellitus
It is unknown whether elevated maternal low-density lipoprotein cholesterol (LDL-C) levels lead to dyslipidemia in the offspring. Because this could have important consequences for cardiovascular prevention in mother and child, we explored the relationship between maternal familial hypercholesterolemia (FH) and lipids in adult offspring.
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