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Plasma Phospholipid Transfer Protein Deficiency in Mice Is Associated With a Reduced Thrombotic Response to Acute Intravascular Oxidative Stress
Author(s) -
Catherine Desrumaux,
Valérie Deckert,
Stéphanie LemaireEwing,
Claude Mossiat,
Anne Athias,
David Vandroux,
Laure Dumont,
Serge Monier,
Jean-Paul Paı̈s de Barros,
Alexis Klein,
Emmanuel de Maistre,
Denis Blache,
A. Beley,
Christine Marie,
Philippe Garnier,
Laurent Lagrost
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.207654
Subject(s) - oxidative stress , medicine , phospholipid , oxidative phosphorylation , phospholipid transfer protein , cardiology , chemistry , biochemistry , membrane
Earlier in vitro studies suggested a putative role for the plasma phospholipid transfer protein (PLTP) in the modulation of blood coagulation. The effect of PLTP expression on blood coagulation under both basal and oxidative stress conditions was compared here in wild-type and PLTP-deficient (PLTP-/-) mice.

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