Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis
Author(s) -
Kiyuk Chang,
Sanjeev Francis,
Elena Aïkawa,
JoseLuiz Figueiredo,
Rainer H. Köhler,
Jason R. McCarthy,
Ralph Weissleder,
Jorge Plutzky,
Farouc A. Jaffer
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.206342
Subject(s) - in vivo , intravital microscopy , inflammation , matrix metalloproteinase , pioglitazone , medicine , pathology , chemistry , endocrinology , diabetes mellitus , biology , microcirculation , type 2 diabetes , microbiology and biotechnology
To investigate the effects of pioglitazone (PIO), a peroxisome proliferator-activated receptor γ agonist, on plaque matrix metalloproteinase (MMP) and macrophage (Mac) responses in vivo in a molecular imaging study.
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