Open AccessDevelopment of Spontaneous Anergy in Invariant Natural Killer T Cells in a Mouse Model of Dyslipidemia
Author(s) -
Nicole Braun,
Yanice Mendez-Fernandez,
Roman Covarrubias,
Steven A. Porcelli,
Paul B. Savage,
Hideo Yagita∥,
Luc Van Kaer,
Amy S. Major
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.206045
Subject(s) - cd1d , natural killer t cell , t cell , biology , immunology , microbiology and biotechnology , cytokine , immune system
In this study, we investigated whether dyslipidemia-associated perturbed invariant natural killer T (iNKT) cell function is due to intrinsic changes in iNKT cells or defects in the ability of antigen-presenting cells to activate iNKT cells.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom