Derivation of Endothelial Cells From Human Embryonic Stem Cells by Directed Differentiation
Author(s) -
Nicole M. Kane,
Marco Meloni,
Helen Spencer,
Margaret Anne Craig,
Raimund Strehl,
Graeme Milligan,
Miles D. Houslay,
Joanne C. Mountford,
Costanza Emanueli,
Andrew H. Baker
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.110.204800
Subject(s) - matrigel , microbiology and biotechnology , angiogenesis , embryoid body , cd31 , embryonic stem cell , endothelial stem cell , biology , vasculogenesis , cellular differentiation , regenerative medicine , stem cell , vascular endothelial growth factor , immunology , adult stem cell , cancer research , progenitor cell , in vitro , genetics , gene , vegf receptors
To develop an embryoid body-free directed differentiation protocol for the rapid generation of functional vascular endothelial cells derived from human embryonic stem cells (hESCs) and to assess the system for microRNA regulation and angiogenesis.
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