Propionyl- l -Carnitine Improves Postischemic Blood Flow Recovery and Arteriogenetic Revascularization and Reduces Endothelial NADPH-Oxidase 4–Mediated Superoxide Production | Zendy

Maria Antonietta Stasi | Zendy; Maria Giovanna Scioli | Zendy; Gaetano Arcuri | Zendy; Giovan Giuseppe Mattera | Zendy; Katia Lombardo | Zendy; Marcella Marcellini | Zendy; Teresa Riccioni | Zendy; Sandro De Falco | Zendy; Claudio Pisano | Zendy; Luigi Giusto Spagnoli | Zendy; Franco Borsini | Zendy; Augusto Orlandi | Zendy

Open Access

Propionyl- l -Carnitine Improves Postischemic Blood Flow Recovery and Arteriogenetic Revascularization and Reduces Endothelial NADPH-Oxidase 4–Mediated Superoxide Production

Author(s) -

Maria Antonietta Stasi,

Maria Giovanna Scioli,

Gaetano Arcuri,

Giovan Giuseppe Mattera,

Katia Lombardo,

Marcella Marcellini,

Teresa Riccioni,

Sandro De Falco,

Claudio Pisano,

Luigi Giusto Spagnoli,

Franco Borsini,

Augusto Orlandi

Publication year - 2010

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.201533

Subject(s) - nadph oxidase , chorioallantoic membrane , superoxide , nitric oxide , endothelium , nitric oxide synthase , medicine , endocrinology , pharmacology , chemistry , angiogenesis , biochemistry , oxidative stress , enzyme

The beneficial effect of the natural compound propionyl-l-carnitine (PLC) on intermittent claudication in patients with peripheral arterial disease is attributed to its anaplerotic function in ischemic tissues, but inadequate information is available concerning action on the vasculature.

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