Histamine H1 Receptor Promotes Atherosclerotic Lesion Formation by Increasing Vascular Permeability for Low-Density Lipoproteins | Zendy

Izabela Rozenberg | Zendy; Susanna H.M. Sluka | Zendy; Lucia Rohrer | Zendy; Janin Hofmann | Zendy; Burkhard Becher | Zendy; Alexander Akhmedov | Zendy; Jorge Soliz | Zendy; Pavani Mocharla | Zendy; Jan Borén | Zendy; Pål Johansen | Zendy; Jan Steffel | Zendy; Takeshi Watanabe | Zendy; Thomas F. Lüscher | Zendy; Felix C. Tanner | Zendy

Open Access

Histamine H1 Receptor Promotes Atherosclerotic Lesion Formation by Increasing Vascular Permeability for Low-Density Lipoproteins

Author(s) -

Izabela Rozenberg,

Susanna H.M. Sluka,

Lucia Rohrer,

Janin Hofmann,

Burkhard Becher,

Alexander Akhmedov,

Jorge Soliz,

Pavani Mocharla,

Jan Borén,

Pål Johansen,

Jan Steffel,

Takeshi Watanabe,

Thomas F. Lüscher,

Felix C. Tanner

Publication year - 2010

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.201079

Subject(s) - vascular permeability , receptor , ldl receptor , inflammation , apolipoprotein e , endocrinology , histamine , bone marrow , aorta , medicine , lipoprotein , apolipoprotein b , chemistry , biology , pathology , immunology , cholesterol , disease

Enhanced endothelial permeability leading to intimal accumulation of low-density lipoproteins (LDL) stimulates the formation of atherosclerotic lesions. Histamine is known to increase vascular permeability. Whether this affects the formation of atherosclerotic lesions, however, remains elusive.

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