Hyaluronic Acid Binding Protein 2 Is a Novel Regulator of Vascular Integrity | Zendy

Nurbek Mambetsariev | Zendy; Tamara Mirzapoiazova | Zendy; Bolot Mambetsariev | Zendy; Saad Sammani | Zendy; Frances E. Len | Zendy; Joe G. N. Garcia | Zendy; Patrick A. Singleton | Zendy

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Hyaluronic Acid Binding Protein 2 Is a Novel Regulator of Vascular Integrity

Author(s) -

Nurbek Mambetsariev,

Tamara Mirzapoiazova,

Bolot Mambetsariev,

Saad Sammani,

Frances E. Len,

Joe G. N. Garcia,

Patrick A. Singleton

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.200451

Subject(s) - regulator , hyaluronic acid , chemistry , microbiology and biotechnology , structural integrity , computational biology , biochemistry , biology , anatomy , engineering , structural engineering , gene

The disruption of the endothelial cell barrier is a critical feature of inflammation and an important contributing factor to acute lung injury (ALI), an inflammatory condition that is a major cause of morbidity and mortality in critically ill patients. We evaluated the role of the extracellular serine protease, hyaluronic acid binding protein 2 (HABP2), in vascular barrier regulation.

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