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Sustained Inhibition of Oxidized Low-Density Lipoprotein Is Involved in the Long-Term Therapeutic Effects of Apheresis in Dialysis Patients
Author(s) -
Yuko TsurumiIkeya,
Kouichi Tamura,
Koichi Azuma,
Hiroshi Mitsuhashi,
Hiromichi Wakui,
Ichiro Nakazawa,
Teruyasu Sugano,
Yasuyuki Mochida,
Toshiaki Ebina,
Nobuhito Hirawa,
Yoshiyuki Toya,
Kazuaki Uchino,
Satoshi Umemura
Publication year - 2010
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.109.200212
Subject(s) - apheresis , medicine , ldl apheresis , fibrinogen , hemodialysis , endothelium , umbilical vein , lipoprotein , nitric oxide , dialysis , brachial artery , endothelial stem cell , gastroenterology , immunology , cardiology , blood pressure , cholesterol , platelet , in vitro , chemistry , biochemistry
Low-density lipoprotein (LDL) apheresis is a potential therapy for conventional therapy-resistant peripheral artery disease. In the present study, we examined the chronic effects of LDL apheresis on clinical parameters in vivo and endothelial cell functions in vitro in hemodialysis patients who had the complication of peripheral artery disease.

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