L-4F Alters Hyperlipidemic (But Not Healthy) Mouse Plasma to Reduce Platelet Aggregation | Zendy

Georgette M. Buga | Zendy; Mohamad Navab | Zendy; Satoshi Imaizumi | Zendy; Srinivasa T. Reddy | Zendy; Babak Yekta | Zendy; Greg Hough | Zendy; Shawn Chanslor | Zendy; G.M. Anantharamaiah | Zendy; Alan M. Fogelman | Zendy

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L-4F Alters Hyperlipidemic (But Not Healthy) Mouse Plasma to Reduce Platelet Aggregation

Author(s) -

Georgette M. Buga,

Mohamad Navab,

Satoshi Imaizumi,

Srinivasa T. Reddy,

Babak Yekta,

Greg Hough,

Shawn Chanslor,

G.M. Anantharamaiah,

Alan M. Fogelman

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.200162

Subject(s) - platelet , endocrinology , medicine , apolipoprotein e , chemistry , thromboxane , hyperlipidemia , apolipoprotein b , thromboxane b2 , platelet aggregation , platelet rich plasma , receptor , cholesterol , biochemistry , biology , diabetes mellitus , disease

Background and Purpose- Hyperlipidemia is associated with platelet hyperreactivity. We hypothesized that L-4F, an apolipoprotein A-I mimetic peptide, would inhibit platelet aggregation in hyperlipidemic mice.

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