PKA-Dependent Phosphorylation of Serum Response Factor Inhibits Smooth Muscle–Specific Gene Expression | Zendy

Alicia L. Blaker | Zendy; Joan M. Taylor | Zendy; Christopher P. Mack | Zendy

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PKA-Dependent Phosphorylation of Serum Response Factor Inhibits Smooth Muscle–Specific Gene Expression

Author(s) -

Alicia L. Blaker,

Joan M. Taylor,

Christopher P. Mack

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.197285

Subject(s) - serum response factor , phosphorylation , myocardin , transcription factor , chromatin immunoprecipitation , biology , microbiology and biotechnology , signal transduction , gene , gene expression , promoter , biochemistry

Our goal was to identify phosphorylation sites that regulate serum response factor (SRF) activity to gain a better understanding of the signaling mechanisms that regulate SRF's involvement in smooth muscle cell (SMC)-specific and early response gene expression.

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