Vitamin D Receptor Activators Induce an Anticalcific Paracrine Program in Macrophages
Author(s) -
Xianwu Li,
Mei Y. Speer,
Hsueh Yang,
Jamie Bergen,
Cecilia M. Giachelli
Publication year - 2009
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.109.196576
Subject(s) - osteopontin , calcitriol receptor , paracrine signalling , calcitriol , calcification , osteoprotegerin , paricalcitol , endocrinology , medicine , macrophage , bone morphogenetic protein 2 , vitamin d and neurology , receptor , secondary hyperparathyroidism , microbiology and biotechnology , biology , cancer research , parathyroid hormone , biochemistry , calcium , in vitro , activator (genetics)
Vascular calcification is highly correlated with morbidity and mortality, and it is often associated with inflammation. Vitamin D may regulate vascular calcification and has been associated with cardiovascular survival benefits.
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