Chylomicronemia Elicits Atherosclerosis in Mice—Brief Report | Zendy

Michael M. Weinstein | Zendy; Liya Yin | Zendy; Yiping Tu | Zendy; Xuping Wang | Zendy; Xiaohui Wu | Zendy; Lawrence W. Castellani | Zendy; Rosemary L. Walzem | Zendy; Aldons J. Lusis | Zendy; Loren G. Fong | Zendy; Anne P. Beigneux | Zendy; Stephen G. Young | Zendy

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Chylomicronemia Elicits Atherosclerosis in Mice—Brief Report

Author(s) -

Michael M. Weinstein,

Liya Yin,

Yiping Tu,

Xuping Wang,

Xiaohui Wu,

Lawrence W. Castellani,

Rosemary L. Walzem,

Aldons J. Lusis,

Loren G. Fong,

Anne P. Beigneux,

Stephen G. Young

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.196329

Subject(s) - lipolysis , medicine , endocrinology , apolipoprotein b , cholesterol , apolipoprotein e , triglyceride , chemistry , biology , disease , adipose tissue

The risk of atherosclerosis in the setting of chylomicronemia has been a topic of debate. In this study, we examined susceptibility to atherosclerosis in Gpihbp1-deficient mice (Gpihbp1(-/-)), which manifest severe chylomicronemia as a result of defective lipolysis.

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