Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators
Author(s) -
Christoph A. Reichel,
Markus Rehberg,
Max Lerchenberger,
Nina Berberich,
Péter Bihari,
Alexander G. Khandoga,
Stefan Zahler,
Fritz Krombach
Publication year - 2009
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.109.193268
Subject(s) - ccl3 , chemokine , ccl2 , intravital microscopy , chemotaxis , chemistry , leukotriene b4 , ccl4 , downregulation and upregulation , leukotriene , monocyte , cxcl2 , platelet activating factor , inflammation , immunology , microbiology and biotechnology , biology , in vivo , biochemistry , chemokine receptor , receptor , carbon tetrachloride , organic chemistry , asthma , gene
Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1alpha (Ccl3/MIP-1alpha) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
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