Liver X Receptor–Mediated Induction of Cholesteryl Ester Transfer Protein Expression Is Selectively Impaired in Inflammatory Macrophages | Zendy

Daniela Lakomy | Zendy; Cédric Rébé | Zendy; Anne-Laure Sberna | Zendy; David Masson | Zendy; Thomas Gautier | Zendy; Angélique Chevriaux | Zendy; Magalie Raveneau | Zendy; Nicolas Ogier | Zendy; Anh Thoai Nguyen | Zendy; Philippe Gambert | Zendy; Jacques Grober | Zendy; Bernard Bonnotte | Zendy; Éric Solary | Zendy; Laurent Lagrost | Zendy

Open Access

Liver X Receptor–Mediated Induction of Cholesteryl Ester Transfer Protein Expression Is Selectively Impaired in Inflammatory Macrophages

Author(s) -

Daniela Lakomy,

Cédric Rébé,

Anne-Laure Sberna,

David Masson,

Thomas Gautier,

Angélique Chevriaux,

Magalie Raveneau,

Nicolas Ogier,

Anh Thoai Nguyen,

Philippe Gambert,

Jacques Grober,

Bernard Bonnotte,

Éric Solary,

Laurent Lagrost

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.193201

Subject(s) - abcg1 , cholesterylester transfer protein , abca1 , liver x receptor , endocrinology , agonist , inflammation , medicine , chemistry , macrophage , downregulation and upregulation , cholesteryl ester , monocyte , reverse cholesterol transport , biology , cholesterol , receptor , lipoprotein , nuclear receptor , biochemistry , in vitro , transporter , gene , transcription factor

Cholesteryl ester transfer protein (CETP) is a target gene for the liver X receptor (LXR). The aim of this study was to further explore this regulation in the monocyte-macrophage lineage and its modulation by lipid loading and inflammation, which are key steps in the process of atherogenesis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research