Genome-Wide Association Identifies the ABO Blood Group as a Major Locus Associated With Serum Levels of Soluble E-Selectin
Author(s) -
Andrew D. Paterson,
Maria F. LopesVirella,
Daryl Waggott,
Andrew P. Boright,
S. Mohsen Hosseini,
Rickey E. Carter,
Enqing Shen,
Lucia Mirea,
Bhupinder Bharaj,
Lei Sun,
Shelley B. Bull
Publication year - 2009
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.109.192971
Subject(s) - abo blood group system , locus (genetics) , genome wide association study , biology , genetics , genetic association , genome , immunology , genotype , gene , single nucleotide polymorphism
Elevated serum soluble E-selectin levels have been associated with a number of diseases. Although E-selectin levels are heritable, little is known about the specific genetic factors involved. E-selectin levels have been associated with the ABO blood group phenotype.
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