Protective Role of Clusterin/Apolipoprotein J Against Neointimal Hyperplasia via Antiproliferative Effect on Vascular Smooth Muscle Cells and Cytoprotective Effect on Endothelial Cells | Zendy

Han-Jong Kim | Zendy; Eun-Kyung Yoo | Zendy; Joon-Young Kim | Zendy; Young-Keun Choi | Zendy; HyoJeong Lee | Zendy; Jeong-Kook Kim | Zendy; Nam Ho Jeoung | Zendy; KiUp Lee | Zendy; In-Sun Park | Zendy; Bon-Hong Min | Zendy; KeunGyu Park | Zendy; ChulHo Lee | Zendy; Bruce J. Aronow | Zendy; Masataka Sata | Zendy; InKyu Lee | Zendy

Open Access

Protective Role of Clusterin/Apolipoprotein J Against Neointimal Hyperplasia via Antiproliferative Effect on Vascular Smooth Muscle Cells and Cytoprotective Effect on Endothelial Cells

Author(s) -

Han-Jong Kim,

Eun-Kyung Yoo,

Joon-Young Kim,

Young-Keun Choi,

HyoJeong Lee,

Jeong-Kook Kim,

Nam Ho Jeoung,

KiUp Lee,

In-Sun Park,

Bon-Hong Min,

KeunGyu Park,

ChulHo Lee,

Bruce J. Aronow,

Masataka Sata,

InKyu Lee

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.190058

Subject(s) - clusterin , neointimal hyperplasia , vascular smooth muscle , smooth muscle , cancer research , chemistry , microbiology and biotechnology , apoptosis , medicine , restenosis , biology , biochemistry , stent

Clusterin is induced in vascular smooth muscle cells (VSMCs) during atherosclerosis and injury-induced neointimal hyperplasia. However, its functional roles in VSMCs and endothelial cells remain controversial and elusive. This study was undertaken to clarify the role of clusterin in neointimal hyperplasia and elucidate its mechanism of action.

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