Imaging and Quantitative Analysis of Atherosclerotic Lesions by CARS-Based Multimodal Nonlinear Optical Microscopy
Author(s) -
Han-Wei Wang,
Ingeborg M. Langohr,
Michael Sturek,
JiXin Cheng
Publication year - 2009
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.109.189316
Subject(s) - microscopy , lesion , autofluorescence , optical microscope , fluorescence microscope , pathology , biomedical engineering , materials science , lipid droplet , chemistry , optics , medicine , fluorescence , scanning electron microscope , composite material , physics
The purpose of this study was to assess the ability of label-free multimodal nonlinear optical (NLO) microscopy to characterize, and thus enable quantitative in situ analyses of, different atherosclerotic lesion types, according to the original scheme suggested by the AHA Committee.
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