Sphingomyelin Synthase 2 Is One of the Determinants for Plasma and Liver Sphingomyelin Levels in Mice | Zendy

Jing Liu | Zendy; Hongqi Zhang | Zendy; Zhiqiang Li | Zendy; Tiruneh Hailemariam | Zendy; Mahua Chakraborty | Zendy; Kailiu Jiang | Zendy; Daniel Qiu | Zendy; Hai H. Bui | Zendy; David A. Peake | Zendy; MingShang Kuo | Zendy; Raj Wadgaonkar | Zendy; Guoqing Cao | Zendy; XianCheng Jiang | Zendy

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Sphingomyelin Synthase 2 Is One of the Determinants for Plasma and Liver Sphingomyelin Levels in Mice

Author(s) -

Jing Liu,

Hongqi Zhang,

Zhiqiang Li,

Tiruneh Hailemariam,

Mahua Chakraborty,

Kailiu Jiang,

Daniel Qiu,

Hai H. Bui,

David A. Peake,

MingShang Kuo,

Raj Wadgaonkar,

Guoqing Cao,

XianCheng Jiang

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.109.185223

Subject(s) - sphingomyelin , medicine , endocrinology , lipoprotein , chemistry , cholesterol , ceramide , knockout mouse , sphingolipid , sphingomyelin phosphodiesterase , in vivo , metabolism , biology , biochemistry , receptor , apoptosis , microbiology and biotechnology

It has been proposed that plasma sphingomyelin (SM) plays a very important role in plasma lipoprotein metabolism and atherosclerosis. Sphingomyelin synthase (SMS) is the last enzyme for SM de novo biosynthesis. Two SMS genes, SMS1 and SMS2, have been cloned and characterized.

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