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Role of 3β-Hydroxysteroid-Δ24 Reductase in Mediating Antiinflammatory Effects of High-Density Lipoproteins in Endothelial Cells
Author(s) -
Kristine McGrath,
X.H. Li,
Rajesh Puranik,
E Liong,
Joanne T. M. Tan,
Veronica Dy,
Belinda A. Di Bartolo,
Philip J. Barter,
K.-A. Rye,
Alison K. Heather
Publication year - 2009
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.109.184663
Subject(s) - downregulation and upregulation , endocrinology , gene silencing , medicine , p50 , tumor necrosis factor alpha , nf κb , inflammation , reductase , biology , chemistry , enzyme , transcription factor , gene , biochemistry
The purpose of this study was to investigate the ability of high-density lipoproteins (HDLs) to upregulate genes with the potential to protect against inflammation in endothelial cells.

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