Role of 3β-Hydroxysteroid-Δ24 Reductase in Mediating Antiinflammatory Effects of High-Density Lipoproteins in Endothelial Cells
Author(s) -
Kristine McGrath,
X.H. Li,
Rajesh Puranik,
E Liong,
Joanne T. M. Tan,
Veronica Dy,
Belinda A. Di Bartolo,
Philip J. Barter,
K.-A. Rye,
Alison K. Heather
Publication year - 2009
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.109.184663
Subject(s) - downregulation and upregulation , endocrinology , gene silencing , medicine , p50 , tumor necrosis factor alpha , nf κb , inflammation , reductase , biology , chemistry , enzyme , transcription factor , gene , biochemistry
The purpose of this study was to investigate the ability of high-density lipoproteins (HDLs) to upregulate genes with the potential to protect against inflammation in endothelial cells.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom