Antiplatelet Actions of Statins and Fibrates Are Mediated by PPARs | Zendy

Ferhana Y. Ali | Zendy; Paul C. Armstrong | Zendy; A. Dhanji | Zendy; Arthur Tucker | Zendy; Mark J. PaulClark | Zendy; Jane A. Mitchell | Zendy; Timothy D. Warner | Zendy

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Antiplatelet Actions of Statins and Fibrates Are Mediated by PPARs

Author(s) -

Ferhana Y. Ali,

Paul C. Armstrong,

A. Dhanji,

Arthur Tucker,

Mark J. PaulClark,

Jane A. Mitchell,

Timothy D. Warner

Publication year - 2009

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.108.183160

Subject(s) - fenofibrate , simvastatin , platelet , pharmacology , platelet activation , peroxisome proliferator activated receptor , fluvastatin , arachidonic acid , antagonist , medicine , ex vivo , pravastatin , endocrinology , chemistry , receptor , in vitro , cholesterol , biochemistry , enzyme

Statins and fibrates are hypolipidemic drugs which decrease cardiac events in individuals without raised levels of cholesterol. These drugs inhibit platelet function, but the mechanisms by which this pleiotropic effect is exerted are not known.

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