Leukotriene Receptor Antagonism and the Prevention of Extracellular Matrix Degradation During Atherosclerosis and In-Stent Stenosis
Author(s) -
Hanna Hlawaty,
MariePaule Jacob,
Liliane Louedec,
Didier Letourneur,
Charles Brink,
JeanBaptiste Michel,
Laurent J. Feldman,
Magnus Bäck
Publication year - 2009
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.108.181750
Subject(s) - medicine , intimal hyperplasia , restenosis , angioplasty , stent , stenosis , neointima , coronary arteries , endocrinology , cardiology , artery , smooth muscle
The lipid-derived inflammatory mediators leukotrienes (LTs) are produced during vascular injury. The aim of the present study was to determine the role of LT receptor signaling in the pathophysiology of in-stent stenosis.
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