Open AccessTorcetrapib Differentially Modulates the Biological Activities of HDL2 and HDL3 Particles in the Reverse Cholesterol Transport Pathway
Author(s) -
Giovanna Catalano,
Zélie Julia,
Éric Frisdal,
Benoît Védie,
Natalie Fournier,
Wilfried Le Goff,
M. John Chapman,
Maryse Guérin
Publication year - 2008
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.108.179416
Subject(s) - cholesterylester transfer protein , medicine , abcg1 , endocrinology , chemistry , apolipoprotein b , reverse cholesterol transport , cholesterol , hyperlipidemia , pitavastatin , endogeny , atorvastatin , lipoprotein , pharmacology , biochemistry , abca1 , diabetes mellitus , transporter , gene
Therapeutic strategies to raise low plasma HDL-cholesterol levels, with concomitant normalization of the intravascular metabolism, physicochemical properties, and antiatherogenic function of HDL particles, are a major focus in atherosclerosis prevention.
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