Open AccessAbsence of Hyperlipidemia in LDL Receptor-Deficient Mice Having Apolipoprotein B100 Without the Putative Receptor-Binding Sequences
Author(s) -
Lance A. Johnson,
Michael K. Altenburg,
Rosemary L. Walzem,
Lori Scanga,
Nobuyo Maeda
Publication year - 2008
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.108.169680
Subject(s) - hyperlipidemia , apolipoprotein b , ldl receptor , receptor , medicine , endocrinology , apolipoprotein e , chemistry , biology , cholesterol , lipoprotein , diabetes mellitus , disease
To examine the effects of apoB100 structure, specifically a mutation in the LDLr binding region, on the production of LDL and development of atherosclerosis in vivo.
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