Overexpression of Human ABCG1 Does Not Affect Atherosclerosis in Fat-Fed ApoE-Deficient Mice
Author(s) -
Braydon L. Burgess,
Kathryn E. Naus,
Jeniffer Chan,
Veronica HirschReinshagen,
Gavin Tansley,
Lisa Matzke,
Benny K. K. Chan,
Anna Wilkinson,
Jianjia Fan,
James Donkin,
Danielle Balik,
Tracie Tanaka,
George Ou,
Roger Dyer,
Sheila M. Innis,
Bruce M. McManus,
Dieter Lütjohann,
Cheryl L. Wellington
Publication year - 2008
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.108.168542
Subject(s) - abcg1 , abca1 , cholesterol , genetically modified mouse , desmosterol , endocrinology , lathosterol , medicine , apolipoprotein e , lanosterol , transgene , biology , lipoprotein , sterol , endogeny , chemistry , biochemistry , campesterol , transporter , gene , disease
The purpose of this study was to evaluate the effects of whole body overexpression of human ABCG1 on atherosclerosis in apoE(-/-) mice.
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