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Polymorphisms of the IL1-Receptor Antagonist Gene ( IL1RN ) Are Associated With Multiple Markers of Systemic Inflammation
Author(s) -
Alexander P. Reiner,
Mark M. Wurfel,
Leslie A. Lange,
Christopher S. Carlson,
Alex S. Nord,
Cara L. Carty,
Mark J. Rieder,
Cindy Desmarais,
Nancy S. Jenny,
Carlos Iribarren,
Jeremy Walston,
O. Dale Williams,
Deborah A. Nickerson,
Gail P. Jarvik
Publication year - 2008
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.108.167437
Subject(s) - interleukin 1 receptor antagonist , allele , systemic inflammation , inflammation , haplotype , immunology , biology , acute phase protein , fibrinogen , gene , gene polymorphism , minor allele frequency , allele frequency , medicine , receptor antagonist , genetics , receptor , antagonist
Circulating levels of acute phase reactant proteins such as plasma C-reactive protein (CRP) are likely influenced by multiple genes regulating the innate immune response.

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