Complete Downmodulation of P-Selectin Glycoprotein Ligand in Monocytes Undergoing Apoptosis | Zendy

Jan-Julius Stampfuss | Zendy; Petra Censarek | Zendy; Jens W. Fischer | Zendy; Gernot Kaber | Zendy; Bernhard Rauch | Zendy; Kerstin Freidel | Zendy; Ute Fischer | Zendy; Klaus SchulzeOsthoff | Zendy; Tilo Großer | Zendy; Maria Grandoch | Zendy; Karsten Schrör | Zendy; ArturAron Weber | Zendy

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Complete Downmodulation of P-Selectin Glycoprotein Ligand in Monocytes Undergoing Apoptosis

Author(s) -

Jan-Julius Stampfuss,

Petra Censarek,

Jens W. Fischer,

Gernot Kaber,

Bernhard Rauch,

Kerstin Freidel,

Ute Fischer,

Klaus SchulzeOsthoff,

Tilo Großer,

Maria Grandoch,

Karsten Schrör,

ArturAron Weber

Publication year - 2008

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.108.166629

Subject(s) - flow cytometry , microbiology and biotechnology , apoptosis , monocyte , chemistry , biology , immunology , biochemistry

Apoptotic monocytes release membrane microparticles which may play a major role in thrombogenicity through a P-selectin glycoprotein ligand (PGSL-1)-mediated mechanism. We have studied systematically the regulation of PSGL-1 expression and function in apoptotic monocytic cells.

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