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Intracellular Localization of Cthrc1 Characterizes Differentiated Smooth Muscle
Author(s) -
Renée J. LeClair,
Qiaozeng Wang,
Meredith A. Benson,
Igor Prudovsky,
Volkhard Lindner
Publication year - 2008
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.108.166579
Subject(s) - extracellular , intracellular , microbiology and biotechnology , cytoplasm , neointima , vascular smooth muscle , myocyte , chemistry , plasmin , biology , biochemistry , medicine , endocrinology , smooth muscle , enzyme , restenosis , stent
We recently reported expression of collagen triple helix repeat containing-1 (Cthrc1) in injured arteries and proteolytic cleavage of Cthrc1 in smooth muscle cells in vitro. The present study characterizes Cthrc1 processing and determines its biological significance.

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