Overexpression of ACE2 Enhances Plaque Stability in a Rabbit Model of Atherosclerosis | Zendy

Bo Dong | Zendy; Cheng Zhang | Zendy; Jing Bo Feng | Zendy; Yu Zhao | Zendy; Shu Ying Li | Zendy; Ya Pei Yang | Zendy; Qiu Dong | Zendy; Bi Ping Deng | Zendy; Li Zhu | Zendy; Qing Yu | Zendy; Chun Xi Liu | Zendy; Bin Liu | Zendy; Chun Pan | Zendy; Huai Dong Song | Zendy; Ming Xiang Zhang | Zendy; Yun Zhang | Zendy

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Overexpression of ACE2 Enhances Plaque Stability in a Rabbit Model of Atherosclerosis

Author(s) -

Bo Dong,

Cheng Zhang,

Jing Bo Feng,

Yu Zhao,

Shu Ying Li,

Ya Pei Yang,

Qiu Dong,

Bi Ping Deng,

Li Zhu,

Qing Yu,

Chun Xi Liu,

Bin Liu,

Chun Pan,

Huai Dong Song,

Ming Xiang Zhang,

Yun Zhang

Publication year - 2008

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.108.164715

Subject(s) - angiotensin ii , angiotensin converting enzyme 2 , renin–angiotensin system , medicine , angiotensin ii receptor type 1 , abdominal aorta , recombinant dna , endocrinology , aorta , antagonist , receptor , pharmacology , chemistry , gene , blood pressure , biochemistry , disease , covid-19 , infectious disease (medical specialty)

The purpose of this study was to test the hypothesis that ACE2 overexpression may enhance atherosclerotic plaque stability by antagonizing ACE activity and converting angiotensin II to angiotensin 1-7.

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