Telomere Gap Between Granulocytes and Lymphocytes Is a Determinant for Hematopoetic Progenitor Cell Impairment in Patients With Previous Myocardial Infarction
Author(s) -
Ioakim Spyridopoulos,
Young Erben,
Tim H. Brümmendorf,
Judith Haendeler,
Klaus Dietz,
Florian Seeger,
Christine K. Kissel,
Hans Martin,
Jedrzej Hoffmann,
Birgit Aßmus,
Andreas M. Zeiher,
Stefanie Dimmeler
Publication year - 2008
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.160846
Subject(s) - bone marrow , telomere , progenitor cell , peripheral blood mononuclear cell , medicine , coronary artery disease , peripheral , myocardial infarction , stem cell , cardiology , pathology , immunology , biology , dna , biochemistry , genetics , in vitro
We have previously demonstrated that ischemic cardiomyopathy is associated with selective impairment of progenitor cell function in the bone marrow and in the peripheral blood, which may contribute to an unfavorable left ventricular remodeling process.
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