Open AccessRegulation of Endothelial Cell Proliferation by Primary Monocytes
Author(s) -
Shai Y. Schubert,
Alejandro Benarroch,
Janne Ostvang,
Elazer R. Edelman
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.157537
Subject(s) - primary (astronomy) , microbiology and biotechnology , cell growth , endothelial stem cell , primary cell , immunology , cell , biology , genetics , in vitro , physics , astronomy
Endothelial cell-monocyte cross talk is essential for vascular repair. Monocytes colocalize with endothelial cells forming a complex set of interactions distinct from the growth promoting cytokines secreted by differentiated macrophages. In the present work we examined the growth regulation and in vitro wound repair early after binding of monocytes to endothelial cells.
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