Human C-Reactive Protein Activates Monocyte-Derived Dendritic Cells and Induces Dendritic Cell-Mediated T-Cell Activation | Zendy

Emily A. Van Vré | Zendy; Hidde Bult | Zendy; Vicky Y. Hoymans | Zendy; Viggo Van Tendeloo | Zendy; Christiaan Vrints | Zendy; Johan Bosmans | Zendy

Open Access

Human C-Reactive Protein Activates Monocyte-Derived Dendritic Cells and Induces Dendritic Cell-Mediated T-Cell Activation

Author(s) -

Emily A. Van Vré,

Hidde Bult,

Vicky Y. Hoymans,

Viggo Van Tendeloo,

Christiaan Vrints,

Johan Bosmans

Publication year - 2008

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.107.157016

Subject(s) - cd86 , cd80 , cd40 , dendritic cell , flow cytometry , t cell , immunology , c reactive protein , antigen , monocyte , secretion , chemistry , microbiology and biotechnology , biology , endocrinology , inflammation , immune system , in vitro , cytotoxic t cell , biochemistry

Recent studies proposed a pathogenic role for C-reactive protein (CRP), an independent predictor of cardiovascular disease (CVD), in atherosclerosis. Therefore, we tested whether CRP may modulate dendritic cell (DC) function, because these professional antigen-presenting cells have been implicated in atherogenesis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research