TF/FVIIa Transactivate PDGFRβ to Regulate PDGF-BB–Induced Chemotaxis in Different Cell Types | Zendy

Agneta Siegbahn | Zendy; Matilda Johnell | Zendy; Anordin | Zendy; Mikael Åberg | Zendy; Teet Velling | Zendy

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TF/FVIIa Transactivate PDGFRβ to Regulate PDGF-BB–Induced Chemotaxis in Different Cell Types

Author(s) -

Agneta Siegbahn,

Matilda Johnell,

Anordin,

Mikael Åberg,

Teet Velling

Publication year - 2007

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.107.155754

Subject(s) - platelet derived growth factor receptor , chemotaxis , microbiology and biotechnology , platelet derived growth factor , chemistry , cancer research , receptor , biology , growth factor , biochemistry

We have previously reported the potentiation of PDGF-BB-induced chemotaxis of fibroblasts, vascular smooth muscle cells, and endothelial cells by FVIIa. Here we studied the role of TF/FVIIa and the induced signaling pathways in regulation of chemotaxis of human monocytes, fibroblasts, and porcine aorta endothelial cells.

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