Open AccessPlasminogen Activator Inhibitor-1 Polymorphism (4G/5G) Predicts Recurrence in Nonhyperlipidemic Postinfarction Patients
Author(s) -
James P. Corsetti,
Dan Ryan,
Arthur J. Moss,
David L. Rainwater,
Wojciech Zaręba,
Charles E. Sparks
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.155556
Subject(s) - medicine , hazard ratio , myocardial infarction , plasminogen activator inhibitor 1 , allele , plasminogen activator , gene polymorphism , population , proportional hazards model , oncology , gastroenterology , confidence interval , biology , genetics , gene , environmental health
Nonhyperlipidemic postinfarction patients are at high risk for recurrent coronary events by virtue of incident myocardial infarction (MI); however, few studies assess risk beyond incident MI. The aim of this study was to assess such risk as a function of 37 atherosclerosis-associated genetic polymorphisms and 17 blood marker variables.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom