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Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR −/− Mice
Author(s) -
Marcella van Leeuwen,
Marion J. Gijbels,
Adriaan Duijvestijn,
Marjan Smook,
Marie José van de Gaar,
Peter Heeringa,
Menno P.J. de Winther,
Jan Willem Cohen Tervaert
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.154807
Subject(s) - myeloperoxidase , ldl receptor , inflammation , chemistry , medicine , pathology , immunology , cholesterol , lipoprotein
Atherosclerosis is a chronic inflammatory disease in which the immune system plays an important role. Neutrophils have not been thoroughly studied in the context of atherogenesis. Here, we investigated neutrophils in the development of murine atherosclerotic lesions.

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