Open AccessIL-6 Deficiency Protects Against Angiotensin II–Induced Endothelial Dysfunction and Hypertrophy
Author(s) -
Laura I. Schrader,
Dale A. Kinzenbaw,
Andrew Johnson,
Frank M. Faraci,
Sean P. Didion
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.153080
Subject(s) - endothelial dysfunction , angiotensin ii , medicine , muscle hypertrophy , endocrinology , renin–angiotensin system , endothelium , blood pressure
The goal of this study was to test the hypothesis that IL-6 mediates the increases in superoxide, vascular hypertrophy, and endothelial dysfunction in response to angiotensin II (Ang II).
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