Open AccessSequential Activation of Matrix Metalloproteinase 9 and Transforming Growth Factor β in Arterial Elastocalcinosis
Author(s) -
Céline Bouvet,
Simon Moreau,
Joannie Blanchette,
Denis de Blois,
Pierre Moreau
Publication year - 2008
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.153056
Subject(s) - matrix metalloproteinase , matrix metalloproteinase 9 , transforming growth factor , medicine , metalloproteinase , cardiology , endocrinology , biology
Isolated systolic hypertension is associated with increased elastase activity, vascular calcification, and vascular stiffness. We sought to determine the importance of elastase activity and matrix degradation in the development of elastocalcinosis.
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