Critical Role of Bone Marrow Angiotensin II Type 1 Receptor in the Pathogenesis of Atherosclerosis in Apolipoprotein E–Deficient Mice | Zendy

Daiju Fukuda | Zendy; Masataka Sata | Zendy; Nobukazu Ishizaka | Zendy; Ryozo Nagai | Zendy

Open Access

Critical Role of Bone Marrow Angiotensin II Type 1 Receptor in the Pathogenesis of Atherosclerosis in Apolipoprotein E–Deficient Mice

Author(s) -

Daiju Fukuda,

Masataka Sata,

Nobukazu Ishizaka,

Ryozo Nagai

Publication year - 2007

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.107.152363

Subject(s) - pathogenesis , bone marrow , apolipoprotein e , angiotensin ii , apolipoprotein b , receptor , medicine , biology , endocrinology , immunology , disease , cholesterol

It is suggested that the angiotensin II (Ang II)-Ang II type 1 receptor (AT1R) pathway plays a pivotal role in the pathogenesis of atherosclerosis. Recently, bone marrow (BM) cells were reported to express AT1R. Here, we investigated the role of AT1R in BM in the pathogenesis of atherosclerosis.

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